Thursday, 23 July 2015

IAS 2015: Reaching 90-90-90

AFAO Policy Analyst, Michael Frommer discusses day one of IAS 2015.

Questions about the best way to facilitate access to testing in order to reach the UNAIDS target of 90% of people with HIV diagnosed was a recurring theme in sessions on the first day of IAS 2015,  Vancouver.

Dr Anthony Fauci of the National Institute of Health (US) provided an overview in his address, 'Progress and Challenges in HIV Prevention: Vaccine and Non-Vaccine Approaches'.

He argued that there is a direct equivalent to the continuum of care for HIV positive people, with a continuum of care relevant to HIV negative people too - the prevention continuum. Part of the prevention continuum is ongoing outreach - as well as the HIV prevention toolbox, which includes the prevention of mother-to-child transmission (PMTC), pre- and post exposure prophylaxis (PrEP and PEP) and treatment as prevention (TasP).

Dr Anthony Fauci from the National Institute of Health discusses
progress and challenges in HIV prevention
He pointed to the START study results, which show that for people who commenced ART with CD4 counts higher than 500 vs 350 or below, there was a 53% decrease in serious illness and AIDS and non-AIDS-related death.

He also highlighted some of the vaccine studies, saying that although these studies are not  showing high enough efficacy yet (for example, the phase three HIV vaccine trial RV144 only had 31% efficacy)  he said that studies such as RV144 are laying the ground for more efficacious HIV vaccines in the future.

In democratising HIV testing to reach 90-90-90, Badara Samb from UNAIDS explained that the greatest challenge to meeting the 90% target of all HIV-positive people knowing their status, is that there are almost 50% who still do not know their status - around 17.1 million people.

He pointed to evidence which shows that with every 5km that a testing facility is from the target population, there is a decrease of 15% in the number of people testing, demonstrating how essential it is, literally, to bring testing to where people are at. Likewise, he emphasised how essential it is to target key affected populations. He argued that part of the solution is to promote self-testing, while recognising the challenges in relation to efficacy.

Dr Trevor Peter, from the Clinton Foundation whose address focused on New Diagnostics to Advance HIV Testing, explained that there is large amount of evidence showing a high level of misinterpretation of community-administered rapid HIV test results.

Joseph Amon from Human Rights Watch, presented on Enhanced HIV Testing in Context of Human Rights. He highlighted that since 1996 (and updated in 2016), UNAIDS and the Office of the High Commissioner for Human Rights has produced the International Guidelines on HIV/AIDS and Human Rights, which outline the need for HIV testing to be done with consent, and that individuals have the right to high-quality HIV testing.

Issues relating to self-testing were also featured, with arguments that there is a need for much better dissemination of information about the option, while also addressing the need for linkage to care.

With the increasing array of testing options, and expanded settings including more in community, there was a palpable sense of optimism about increasing rates of HIV testing, to work towards the UNAIDS targets.

Michael Frommer, AFAO Policy Analyst, is blogging live from IAS 2015.

9 comments:

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    ReplyDelete
    Replies
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  4. Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Cancer,Hiv_ Aids,Herpes,Copd,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man.

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  5. HPV cure with the help of a herbal medication by Dr Ben for help contact now to get your own cure

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